Pain comes from activation of areas associated with emotion and attention. The anterior cingulate cortex is particularly active when pain is registered. (Carter, Rita, Ed. Mapping the Mind. P33, 100. CA: University of California Press, 1998.)

The Periaqueductal gray, a structure located in the limbic system (or emotional brain), contains many opiate receptors and is involved in the perception of pain. (Candace Pert, Candace, PhD. Molecules of Emotion. Audio Cassettes. NY: Sound Ideas, 1997.)

The Periaqueductal is the pain center. It contains the same peptide receptors that are present elsewhere in the brain. (Pert, Candace, PhD. Your Body is Your Subconscious Mind. Audio Cassettes. CO: Sounds True, 2000.)

What seems to be going on in pain alteration (e.g., yogis who through breath training alter perceptions of physical pain, mothers with Lamaze breathing techniques) is that these people are able to plug into their periaqueductal gray, gaining access to it with their conscious intention, and then, I believe, are able to reset their pain thresholds. (Pert, Candace, PhD. Molecules of Emotion. p 186. NY: Scribner, 1997.)

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