Studies by Dr. Berk of Loma Linda University: Beta-Endorphin and Human Growth Hormone increase are associated with both the anticipation of and the experience of mirthful laughter. Reported April 3, 2006. (Berk, Lee S. PhD. Paper presented in an American Physiological Society session at Experimental Biology, 2006.)

Study: anticipation of mirthful laughter reduced the levels of three detrimental stress hormones. Cortisol (termed the steroid stress hormone), epinephrine (also known as adrenaline) and dopac, (the major catabolite of dopamine), were reduced 39, 70 and 38%, respectively (statistically significant compared to the control group). (Laughter Remains Good Medicine. 2009.)

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