Melatonin is the principal hormone secreted by the Pineal gland in the brain and regulates many neuroendocrine functions. The maximum amount of melatonin released in the bloodstream of the elderly is only half of that in young adults. Positive correlations have been found with aging, sleep, jet-lag, cancer, and stress. (Dean, Ward, M.D., and John Morgenthaler and Steven Wm. Fowkes. Smart Drugs II, Melatonin Chapter. Smart Publications. 2000.

Refer to Sleep and the Brain for additional information

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