Guarana is a climbing plant (Paullinia cupana) that is native to the Amazon basin. As a dietary supplement, guarana has been found to be an effective stimulant as it contains about twice the caffeine levels found in coffee beans (about 2–4.5% caffeine in guarana seeds compared to 1–2% for coffee beans). Experimental models, in addition to in vitro assays, have described several biological effects that guarana shares with green tea such as antioxidant and antibacterial effects. It also has been shown to contribute to the onset of seizures in some people. Guarana is a (Gray, Nathan. Guarana intake associated with reduction in metabolic disorders: Study.

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