Studies: marijuana dependence, like dependence on other addictive drugs, is associated with withdrawal symptoms (e. g., irritability, anger, depressed mood, headaches, restlessness, lack of appetite, cravings) that appear to be as severe as those associated with tobacco smoking. Website: (Zickler, Patrick, Staff Writer. Study Demonstrates that Marijuana Smokers Experience Significant Withdrawal. National Institute on Drug Abuse, NIDA NOTES, Volume 17, Number 3, pp 7-10)

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