Fat in fish (or flaxseed oil) can help to protect arteries from clogging and the heart from shutting down, as well as the brain from depression. This may help explain why depression often precedes and predicts heart disease. Hippocrates said it first: food that is good for the heart is likely to be good for the brain. (Carper, Jean. Your Miracle Brain. p 79-81. NY: HarperCollins Publishers, 2000.)